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GreenDust@lemmings.world to Lemmy Shitpost@lemmy.world · 4 days ago

Grapefruit Redbull

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Grapefruit Redbull

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GreenDust@lemmings.world to Lemmy Shitpost@lemmy.world · 4 days ago
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  • RBWells@lemmy.world
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    2 days ago

    I would be shocked if grapefruit flavored red bull contains any part of grapefruit the fruit.

    • Johnmannesca@lemmy.world
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      19 hours ago

      I think the monster one has a little bit

  • SingularEye@lemmy.blahaj.zone
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    2 days ago

    I don’t get it

    • GeneralVincent@lemmy.world
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      1 day ago

      No grapefruit while taking ssri medication

      edit: sorry, this is a bit misleading and an oversimplification

      https://en.wikipedia.org/wiki/Grapefruit–drug_interactions

      • sem@piefed.blahaj.zone
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        1 day ago

        Wait…

        I don’t think that’s true. If it were, they’d put it in the instructions that come with the SSRI medicines.

        And it is not on the list of drugs on this web page. https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix

        • GeneralVincent@lemmy.world
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          1 day ago

          Yup, I made a bad generalization. My bad, and to be clear I’m not a doctor or anything.

          Some SSRIs may have an interaction with grapefruit. But grapefruit interacts with different medications differently, and it’s not based on the class of medication, it’s med specific.

          e.g. Sertraline (Zoloft) is an SSRI and is listed as having an interaction with grapefruit

          https://en.wikipedia.org/wiki/Grapefruit–drug_interactions

          Eta: thanks for calling that out, I’ve learned some interesting things, for example;

          Ketamine: After drinking 200 mL of grapefruit juice daily for five days, the overall absorption of orally ingested ketamine was increased three-fold compared to the control group in a clinical trial. The peak blood ketamine concentration was increased over two-fold.

          • sem@piefed.blahaj.zone
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            1 day ago

            That is so weird. Here is the study: https://pubmed.ncbi.nlm.nih.gov/10890261/

            It was only n=5 but my layperson understanding is that the results were significant.

            Either I’ve never noticed a grapefruit warning (and at one time I read the documentation fully) or Sertraline doesn’t come with one…

  • Zombie@feddit.uk
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    3 days ago

    did redbull really just release a new subliminal social media advert? girl your shitpost base can’t HAVE adverts??

    • athatet@lemmy.zip
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      3 days ago

      Advertisements in my lemmy shitpost community?

      It’s more likely than you think.

  • 🇰 🌀 🇱 🇦 🇳 🇦 🇰 🇮 @pawb.social
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    4 days ago

    Uh… Why not?

    • Donkter@lemmy.world
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      3 days ago

      Lots of answers but I think the explicit joke here is that grapefruit doesn’t work with certain types of antidepressant medications, which redbull’s clients are presumably on.

    • INeedANewUserName@piefed.social
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      4 days ago

      Grapefruit disrupts metabolism by Cytochrome P450 enzymes in the liver. They are widely involved in drug metabolism. https://en.wikipedia.org/wiki/Cytochrome_P450

    • milagemayvary@mstdn.social
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      4 days ago

      @Kolanaki @GreenDust

      2 minute sci-show answer why it isn’t a good idea to mix certain medications & grapefruit.

      Enzymes in grapeftuit can cause some medications in a safe dose to become too effective often in dangerous ways.

      https://www.youtube.com/watch?v=5Nxne8QfIhM

      • 🇰 🌀 🇱 🇦 🇳 🇦 🇰 🇮 @pawb.social
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        4 days ago

        Are any of those drugs in Redbull, tho?

        • GreenDust@lemmings.worldOP
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          4 days ago

          The implication here is that a consumer who is inclined to drink Redbull is likely the type of person who suffers from an affliction for which they are prescribed some sort of mood-regulating medication, many of which negatively synergize with grapefruit enzymes.

    • A_Union_of_Kobolds@lemmy.world
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      4 days ago

      Doesn’t it interact with… I can’t remember if it was ecstasy or some normal medicine

      • 🇰 🌀 🇱 🇦 🇳 🇦 🇰 🇮 @pawb.social
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        4 days ago

        Only thing that came to mind was diabetics can’t usually have grapefruit. Is the joke that redbull enjoyers are diabetic? 🤔

        • GreenDust@lemmings.worldOP
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          4 days ago

          Antidepressants, anxiolytics, stimulants, etc.

          https://en.wikipedia.org/wiki/Grapefruit-drug_interactions#Incomplete_list_of_affected_drugs

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